Clinical Assessment of a HYDRAGLYDE® Regimen

Inclusion Criteria: * Must sign informed consent document; * Vision correctable to 0.1 (LogMAR) or better in each eye at distance with habitual lenses; * Manifest cylinder (at screening) less than or equal to 0.75 diopter (D) in each eye and spectacle add \<+0.50 D in each eye; * Current full-time wearer of spherical samfilcon A, comfilcon A, senofilcon C monthly or senofilcon A 2-week replacement lens within the power range of lens powers available; * Current user of an MPS (excluding OFPM) to care for lenses; * Willing to answer text messages on a daily basis during the study; * Willing to discontinue artificial tears during the study and rewetting drops on the days of study visits; * Use of digital devices (eg, smart phone, tablet, laptop or desktop computer) for 20 consecutive minutes at least twice a week and willing to continue for the duration of the study; * Other protocol specific inclusion criteria may apply. Exclusion Criteria: * Habitual lens wear in an extended wear modality (routinely sleeping in lenses overnight for 1 or more nights per week); * Any anterior segment infection, inflammation, disease or abnormality that contraindicates contact lens wear; * History of herpetic keratitis, corneal surgery or irregular cornea; * Prior refractive surgery; * Any use of systemic or ocular medications for which contact lens wear could be contraindicated as determined by the investigator; * Currently using or have not discontinued Restasis®, Xiidra™ and/or topical steroids within the past 7 days; * Use of mechanical eyelid therapy or eyelid scrubs within 14 days before Visit 1 and not willing to discontinue during the study; * Monocular (only 1 eye with functional vision) or fit with only 1 lens; * Known pregnancy or lactating; * Other protocol specific exclusion criteria may apply.