Sleep-disordered breathing is believed to appear at a high prevalence in end-stage heart failure patients and the presence of sleep-disordered breathing has been associated with increased mortality. This study is designed to investigate prevalence and dynamics of sleep-disordered breathing in end-stage heart failure patients pre and post heart transplantation.
Sleep-disordered breathing is believed to appear at a high prevalence in end-stage heart failure patients and the presence of sleep-disordered breathing has been associated with increased mortality. This study is designed to investigate prevalence and dynamics of sleep-disordered breathing in end-stage heart failure patients pre and post heart transplantation, as this topic is hardly studied yet and previous reports suggest changes in the entity of sleep-disordered breathing through heart transplantation. The circumstances and the impact of sleep-disordered breathing or residuals in heart transplant patients is not well understood yet and will be subject of this study.
Study Type
OBSERVATIONAL
Enrollment
500
Prevalence and dynamic of sleep-disordered breathing after heart transplantation
Herz- und Diabeteszentrum NRW
Bad Oeynhausen, North Rhine-Westphalia, Germany
Apnea Hypopnea Index
Change in Apnea Hypopnea Index (AHI /h) before and after heart transplantation
Time frame: 30 days after heart transplantation
Apnea Index
Change in Apnea Index (AI /h) before and after heart transplantation
Time frame: 30 days after heart transplantation
Hypopnea Index
Change in Hypopnea Index (HI /h) before and after heart transplantation
Time frame: 30 days after heart transplantation
Oxygen Desaturation Index
Change in Oxygen Desaturation (ODI /h) before and after heart transplantation
Time frame: 30 days after heart transplantation
Time SaO2 < 90 (%)
Change in Time SaO2 \< 90 (%) before and after heart transplantation
Time frame: 30 days after heart transplantation
Respiration cycle length
Change in Respiration cycle lengths before and after heart transplantation
Time frame: 30 days after heart transplantation
Health Questionnaires
Change in MLWH questionnaire, this questionnaires obtains patient's quality of life in a score (in points)
Time frame: 30 days after heart transplantation
Health Questionnaires
ESS questionnaire, this questionnaires obtains patient's sleepiness in daily life in a score (in points)
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Time frame: 30 days after heart transplantation
Health Questionnaires
Short Form 12 Health Survey Questionnaire, this questionnaires obtains patient's health status in a score (in points)
Time frame: 30 days after heart transplantation
Right heart catheter
Changes in right heart catheter before and after heart transplantation
Time frame: 30 days after heart transplantation
Blood gas analysis
Changes in blood gas analyses before and after heart transplantation
Time frame: 30 days after heart transplantation