Blood Flow Change After Free Flap Surgery in Diabetic Patients

Asan Medical Center44 enrolled

Overview

We aim to evaluate the flow change of arterial anastomosis site during free flap surgery in diabetic patients.

Objective: flow change of arterial anastomosis site during free flap surgery in diabetic patients. Background: No research was published about flow change of arterial anastomosis site of the free flap during surgery. Plan: Using Duplex sonography, various parameters related flap perfusion will be evaluated before and after the administration of alprostadil.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Diabetes

Interventions

AlprostadilDRUG

Vasodilator for anastomosis-site of free flap

Eligibility

Sex: ALLMin age: 18 YearsMax age: 79 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Plan to receive free flap transfer under general anesthesia 2. Age: \>=18 and \<80 years old 3. History of diabetes mellitus 4. Administration of alprostadil during surgery 5. Volunteer, who are provided written informed consent prior to study participation Exclusion Criteria: 1. Refuse the participation of study 2. \>= American society of anesthesiologist physical status IV 3. Use of any vasopressor or inotropic for hemodynamic instability before participation of study 4. Inappropriate subjects who are identified by researchers

Locations (1)

Asan Medical Center

Seoul, South Korea

Outcomes

Primary Outcomes

Flow change

Peak velocity of anastomosis-site of free flap

Time frame: before alprostadil administration, 30 mins after alprostadil administration

Data from ClinicalTrials.gov

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