The purpose of this study was to verify the effect of 12-week with β-hydroxy-β-methylbutyrate (HMB) and a placebo (PLA) supplementation on body composition, anaerobic and aerobic capacity, as well as concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.
The effect of HMB supplementation is of great interest in sport. In view of the inconclusive character of the results of the studies conducted to date and of a relatively low number of studies investigating the effectiveness of HMB supplementation over a longer period on a large population of trained athletes, the aim of this study was to verify the effect of 12-week with HMB and a placebo supplementation on body composition, anaerobic and aerobic capacity, as well as concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
58
Poznan University of Life Sciences, ul.Wojska Polskiego 31
Poznan, Wielkopolska, Poland
Changes of body composition indices after HMB supplementation
Analysis of the fat mass and fat free mass
Time frame: Baseline and after 12 weeks
Changes of body composition indices after placebo treatment
Analysis of the fat mass and fat free mass
Time frame: Baseline and after 12 weeks
Changes of aerobic capacity after HMB supplementation
Time frame: Baseline and after 12 weeks
Changes of aerobic capacity after placebo treatment
Time frame: Baseline and after 12 weeks
Changes of anaerobic capacity after HMB supplementation
Time frame: Baseline and after 12 weeks
Changes of anaerobic capacity after placebo treatment
Time frame: Baseline and after 12 weeks
Changes of creatine kinase and lactate dehydrogenase activity in blood after HMB supplementation
Time frame: Baseline and after 12 weeks
Changes of creatine kinase and lactate dehydrogenase activity in blood after placebo treatment
Time frame: Baseline and after 12 weeks
Changes of testosterone, cortisol and lactate levels in blood after HMB supplementation
Time frame: Baseline and after 12 weeks
Changes of testosterone, cortisol and lactate levels in blood after placebo treatment
Time frame: Baseline and after 12 weeks
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Statistical evaluation of the significance of differences between the changes in body composition (fat mass and fat free mass)
Time frame: 1 year
Statistical evaluation of the significance of differences between the changes in aerobic capacity indices
Time frame: 1 year
Statistical evaluation of the significance of differences between the changes in anaerobic capacity indices
Time frame: 1 year
Statistical evaluation of the significance of differences between the changes in creatine kinase and lactate dehydrogenase activity and testosterone, cortisol and lactate levels in blood
Time frame: 1 year