Our trial try to eradicate digestive tract colonization of patient harboring Extreme Drug Resistant (XDR) bacteria by performing a fecal transplantation.
Main objective: Evaluate the eradication of the colonization of patient harboring XDR bacteria after a fecal transplantation from a healthy donor. Secondary objectives: English Evaluate the side effects of this procedure and tolerability. Evaluate the efficacy of the transplant if the patient is harboring glycopeptid resistant enteroccus (GRE) or carbapenem resistant enterobacteriae (CRE)
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
50
We will perform a fecal microbiota transplant for patients harboring XDR bacteria in their digestive tract
Hopital Raymond Poincaré
Garches, France
Negativation of digestive tract colonization
Negativation of the rectal swab performed, free from CRE or GRE
Time frame: At one week, 2 weeks, one month up to 6 months
Metagenomics profile between donor and recipient depending on decolonization
Study with a universal super donor in order to improve efficacy
Time frame: At one week, 2 weeks, one month up to 3 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.