A Double-blind Randomized Placebo Controlled Clinical Trial Evaluating Effect of Chlorhexidine Gluconate 2% Cloth vs Placebo Cloth Baths on the Incidence of Central Line-Associated Blood Stream Infections in Outpatient Hematopoietic Stem Cell Transplant Patients

University of Chicago50 enrolled

Overview

This study evaluates the use of 2% CHG washcloths in an outpatient setting for adults after hematopoietic stem cell transplant in prevention of central line associated blood stream infections. Half of the participants will use 2% CHG washcloths and other half will use placebo washcloths.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

Conditions

Stem Cell Transplant Complications

Interventions

Chlorhexidine Gluconate 2% WipeDRUG

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Admitted to the University of Chicago Hematopoietic Stem Cell Transplant Unit for transplant * Age 18 and up Exclusion Criteria: * Experienced an allergy or rash related to use of chlorhexidine washcloths or other chlorhexidine products * Extensive open wounds

Outcomes

Primary Outcomes

Number of Participants With Primary Blood Stream Infections

Blood stream infections are defined by the presence of bacteria in the blood

Time frame: 14 weeks

Number of Participants With Clinical (Culture-negative) Sepsis

Clinical (culture-negative) sepsis is defined by the presence of low blood pressure without bacteria in the blood