The purpose of this feasibility study is to further explore characteristics of ablation targets identified by CARTOFINDER 4D LAT Algorithm in subjects with persistent atrial fibrillation and to assess the acute outcome of CARTOFINDER Guided Ablation in terms of the termination of atrial fibrillation to either Normal Sinus Rhythm or Atrial Tachycardia.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
25
All enrolled subjects who have ablation targets identified will undergo CARTOFINDER guided ablation (CFGA) followed by PVI. Subjects will be followed per the protocol schedule. Subjects who have no ablation target identified on the baseline CARTOFINDER map will undergo ablation per the institution's standard of care and be followed for 7 days for safety monitoring, then exit from the study.
Evaluate mapping characteristics
Explore characteristics of ablation targets identified by the CARTOFINDER 4D LAT Algorithm
Time frame: Intraoperative
Evaluate acute safety of freedom from procedure-related primary adverse events
Evaluate acute safety of freedom from procedure-related primary adverse events occurring within 7 days of ablation procedure
Time frame: Within 7 days
Evaluate atrial fibrillation (AF) termination
Evaluate the AF termination to Normal Sinus Rhythm (NSR) or an Atrial Tachycardia (AT) after CARTOFINDER™ Guided Ablation (CFGA) of identified ablation target and after PVI
Time frame: Perioperative
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