Purpose: To evaluate the acute and chronic effects of a botanical supplement on strength, muscle function, and lean body mass Participants: The acute phase will include 30 participants, and the chronic phase will include 84 participants. All participants must be healthy recreationally active males between the ages of 18 and 35 years. Procedures (methods): Acute phase: Participants will complete three testing visits as part of as part of a cross-over design, during which strength and muscle function will be assessed prior to and following consumption of a supplement. The experimental supplement is a blend of the botanical extracts; treatment arms will include a full dose (FULL; 350 mg capsule), half dose (HALF; 175 mg plus maltodextrin), or placebo (PLA; maltodextrin). Chronic phase: Body composition, muscle cross-sectional area, a complete blood count and metabolic panel, subjective surveys, and strength will be measured prior to and following an 8-week supervised resistance training program, in conjunction with daily supplementation of FULL, HALF, or PLA.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Enrollment
119
350 mg 'Rhodiola rosea L. \& Rhaptonticum carthamoides extracts
175 mg 'Rhodiola rosea L. \& Rhaptonticum carthamoides extracts + maltodextrin 175 mg
Maltodextrin: 350 mg
University of North Carolina, Department of Exercise and Sport Science
Chapel Hill, North Carolina, United States
Maximal Isokinetic Leg Extension strength measured by dynamometry
Time frame: Acute/Immediate
Maximal Upper and Lower Body Strength measured by 1 repetition maximum
Time frame: 8 weeks
Bench Press Repetitions to Fatigue
Time frame: 8 weeks
Leg Press Repetitions to Fatigue
Time frame: 8 weeks
Body Composition-Lean Mass
Time frame: 8 weeks
Body Composition-Fat Mass
Time frame: 8 weeks
Muscle cross sectional area
Time frame: 8 weeks
Change in Quality of Life Score from baseline to 8 weeks
Quality of life from a visual analog scale (VAS) 0-100, with 0 = worst quality of life and 100=best quality of life.
Time frame: baseline, 8 weeks
Change in Felt Arousal score from baseline to 8 weeks
Felt arousal scale. Scores range 1-6 with 1 being low arousal and 6 being high. One score selected.
Time frame: baseline, 8 weeks
Change in Mood score from baseline to 8 weeks
Mood determined from a VAS. 0-100, with 0 = not depressed at all and 100 = most depressed.
Time frame: baseline; 8 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.