Persona Partial Knee Clinical Outcomes Study

Inclusion Criteria: * Patient is at least 18 years of age * Patient qualifies for knee arthroplasty based upon physical exam and medical history, and meets the approved indications for use of the Persona Partial Knee system. * Patient has participated in a study-related Informed Consent process * Patient is willing and able to provide written Informed Consent by signing and dating the IRB/EC approved Informed Consent form * Patient is willing and able to complete scheduled study procedures and follow-up evaluations * Independent of study participation, patient is a candidate for the commercially available Persona Partial Knee, implanted in accordance with product labeling Exclusion Criteria: * Patient is currently participating in any other surgical intervention studies or pain management studies * Infection, sepsis, and osteomyelitis * Rheumatoid arthritis or other forms of inflammatory joint disease * Insufficiency of the collateral, anterior or posterior cruciate ligaments which would preclude stability of the device * Full thickness damage to the weight bearing area of the contralateral compartment * Uncooperative patient or patient with neurologic disorders who is incapable of following directions * Insufficient bone stock to provide adequate support and/or fixation to the prosthesis * Metabolic disorders which may impair bone formation * Osteomalacia * Distant foci of infections which may spread to the implant site * Rapid joint destruction, marked bone loss or bone resorption apparent on roentgenogram * Vascular insufficiency, muscular atrophy, neuromuscular disease * Incomplete or deficient soft tissue surrounding the knee * Charcot's disease * Fixed varus deformity (not passively correctable) of greater than 15 degrees * Fixed flexion deformity (not passively correctable) of greater than 15 degrees * Patient is pregnant or considered a member of a protected population (e.g., prisoner, mentally incompetent, etc.)