The infantile brain has to pass essential, mayor steps in the first 36 months of life. During that period of development it is particularly vulnerable to toxic, exogenic influences. This study wants to review the long-term effects of children who were exposed to anesthesia in the first three years of their life. Therefore the investigators will examine children at age of 4-10 that were exposed to anesthesia and compare their neurocognitive capacity to children who did not have any exposure to anesthesia. The investigators plan on measuring the intelligence quotient using standardized tests which will be performed by a trained psychologist. In addition there will be a questionnaire concerning behavioral characteristics and educational development which is filled by the parents. The exposed children will be recruited from our preexisting database, the control group will be recruited from practitioners and the pediatric walk-in-clinic.
Study Type
OBSERVATIONAL
Enrollment
700
University Hospital
Erlangen, Bavaria, Germany
Cognitive Capacity for children between 7 and 10 years of age
Standardized tests for intelligence quotient (IQ): Kaufman Assessment Battery for Children - Second Edition (KABC-II)
Time frame: Test is done 1 to 10 years after anesthesia and is lasting 3 hours
Cognitive Capacity for children between 4 and 7 years of age
Standardized tests for intelligence quotient (IQ): Wechsler Preschool and Primary Scale of Intelligence (WPPSI-III)
Time frame: Test is done 1 to 10 years after anesthesia and is lasting 3 hours
Cognitive Capacity for children between 2 and 4 years of age
Standardized tests for intelligence quotient (IQ): Wechsler Intelligence Scale for Children (WISC-IV)
Time frame: Test is done 1 to 10 years after anesthesia and is lasting 3 hours
Educational status
Questionnaire, filled by parents 1-10 years after anesthesia exposure
Time frame: 1 to 10 years after anesthesia, lasting 30 minutes
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