The present study will investigate the effects of a mindfulness training on emotion regulation and social cognition, using several psychological, behavioral, psychophysiological and neuroimaging methods.
The aim of the present study is to evaluate the impact of a mindfulness intervention, particularly the mindfulness-based stress reduction (MBSR), on the capacities of emotion regulation and social cognition, in caring/helping professions which are vulnerable to stress. In the context of a longitudinal intervention study, a randomized controlled trial, the efficacy of the MBSR to increase the capacity for self-emotion regulation, empathic attunement, and compassion capacities will be measured. For doing this, several psychological, behavioral, psychophysiological and neuroimaging brain measurements will be used.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
60
8 week program
8 week program
Berlin School of Mind & Brain, Humboldt Universität.
Berlin, State of Berlin, Germany
RECRUITINGActivation changes in emotions related brain regions. Measured by significant changes in the BOLD (blood oxygenated level dependent) signal from task based functional magnetic resonance imaging.
Time frame: first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention.
Changes in resting state functional connectivity within brain networks. Measured by significant changes in intrinsic functional connectivity parameters, estimated from the resting state BOLD signal, during functional magnetic resonance imaging.
Time frame: first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention.
Changes in resting state functional connectivity between inter-networks connectivity.
Changes between brain networks connectivity (including DMN, fronto-parietal and salience networks), measured as significant changes in inter-networks connectivity parameters estimated from the temporal correlation of intrinsic functional connectivity networks.
Time frame: first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention.
Changes in regional brain morphometry in stress processing related areas. Measured by significant changes in regional grey matter density estimated from structural magnetic resonance imaging.
Time frame: first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention.
Behavioural tasks: mind-wandering task
Changes in mind-wandering task, measured as changes in task-unrelated thoughts.
Time frame: first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention.
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Changes in personality functioning.
Significant changes in levels of personality functioning measured by the operationalized psychodynamic diagnosis scale.
Time frame: first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention.
Experience Sampling of emotional tolerance
Significant changes in self-reported capacity for emotion tolerance.
Time frame: first acquisition period during 3 weeks before the intervention, last acquisition period during 3 weeks after the intervention. And during the intervention period everyday.
Changes in psychophysiological measurements of stress (sympathetic component)
Activation changes in psychophysiological stress parameters using Skin Conductance Response (measured as significant changes in tonic and phasic response levels) during an emotion regulation task.
Time frame: first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention.
Changes in psychophysiological measurements of stress (vagal component)
Activation changes in psychophysiological stress parameters using Heart Rate Variability (power analysis of high frequency sub-bands of heart rate spectrum), during an emotion regulation task.
Time frame: first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention.
Behavioural tasks: empathy test.
Changes in empathy test, measured as changes in levels of cognitive and affective empathy.
Time frame: first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention.
Changes in self-reported affective states
Significant changes in self-reported levels of negative and positive affects measured by the PANAS scale.
Time frame: first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention.
Changes in social functioning
Significant changes in the interpersonal competence questionnaire self-reported scale.
Time frame: first acquisition period during 3 weeks before the intervention, second acquisition period during 3 weeks after the intervention.