Efficacy of Oral Moisturizing Jelly on Oral Health and Nutrition in Post-radiotherapy Head and Neck Cancer Patients

Dental Innovation Foundation Under Royal Patronage73 enrolled

Overview

This randomized control trial aims to investigate the efficacy of oral moisturizing jelly in head and neck cancer patients with xerostomia.

Oral moisturizing jelly is a novel edible, gel-based artificial saliva. It has been proven effective in reducing dry mouth sign and symptoms in elderly patients with xerostomia. This randomized control trial intends to determine if continuous use of oral moisturizing jelly may be effective in reduction of signs and symptoms of dry mouth, improvement of biochemical properties of saliva, subjective swallow ability, appetite, tolerance to spicy food, energy intake and reduce umami taste recognition threshold.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

DOUBLE

Enrollment

Conditions

Cancer of Head Neck Radiation-Induced Xerostomia Dry Mouth

Interventions

Oral moisturizing jellyDIETARY_SUPPLEMENT

Gel-based artificial saliva is an edible non-nutritious gel intended to relieve dry mouth

Artificial salivaOTHER

A non-edible oral lubricating gel for dry mouth patients

Eligibility

Sex: ALLMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Xerostomic head and neck cancer patients who finish radiotherapy for at least 1 month. 2. If undergoing chemotherapy, have to finish for at least 2 weeks. 3. Have subjective dry mouth scores at least 3 4. Can perform oral intake without aspiration 5. Can communicate well Exclusion Criteria: 1. Has recurrence of cancer 2. Has mucositis more than grade 1 3. Has oral infection such as candidiasis

Locations (1)

Chonburi Cancer Hospital

Chon Buri, Changwat Chon Buri, Thailand