Rates of Middle Meatus Synechiae Formation Post ESS

Inclusion Criteria: 1. Age between 18 and 75 years 2. Diagnosis of chronic rhinosinusitis (CRS), per current guidelines 3. Patients who need to undergo primary bilateral complete endoscopic sinus surgery 4. Subject has the ability to follow the study instructions, is willing to be available on the specific required study visit days, and is willing to complete all study visit procedures and assessments 5. Subject must understand the research nature of this study and sign an informed consent prior to the performance of any study-specific procedure or assessment Exclusion Criteria 1. Subject is pregnant or breast feeding 2. Patients with sino-nasal tumors 3. Patients solely undergoing nasal septal reconstruction 4. Patients with previous history of endoscopic sinus surgery 5. Cystic fibrosis or syndromic patients 6. Patients with autoimmune diseases 7. Patients who have taken oral steroids less than 30 days prior to surgery 8. Patients with a history or diagnosis of glaucoma or ocular hypertension 9. Any other circumstance or condition that in the Investigator's opinion causes the subject to be an inappropriate candidate for participating in this study