This study aims to determine the extent to which pre-existing long-term conditions are associated with survival following a heart attack (acute myocardial infarction) using observational data from the UK's national heart attack register.
Using observational data from the Myocardial Ischaemia National Audit Project (MINAP) of all hospitalisations for acute myocardial infarction in all acute hospitals in England and Wales, this study aims to determine the extent to which pre-existing long-term conditions are associated with survival following acute myocardial infarction. The study will include an investigation of individual long term conditions for patients with acute myocardial infarction, including chronic heart failure, cerebrovascular disease, diabetes mellitus, chronic obstructive pulmonary disease, chronic renal failure or peripheral vascular disease as well as the combination of such conditions and their resulting impact on long term all-cause mortality (up to 8.4 years). In addition, an investigation of the association of receipt of guideline recommended care for acute myocardial infarction patients with pre-existing long term conditions will be made.
Study Type
OBSERVATIONAL
Enrollment
693,633
Long term conditions including diabetes mellitus, chronic obstructive pulmonary disease or asthma, chronic heart failure, chronic renal failure, cerebrovascular disease or peripheral vascular disease.
Number of patients who died from any cause by the end of the study censoring period
Death data was obtained from national death records from the Office for National Statistics
Time frame: 8.4 years
Number of patients who received guideline recommended therapy during the study period
All guideline recommended therapies for acute myocardial infarction relevant to the duration of the study period (2003 to 2013) will be assessed.
Time frame: Any guideline therapy administered during the patients hospital admission for acute myocardial infarction, an average of 4 days
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