Demonstrate dose-dependent relationship between vitamin D supplementation and rates of gestational diabetes.
Determine the effect of increased vitamin D supplementation (4000 IU vitamin D3 +prenatal vitamin) on the incidence of gestational diabetes compared to a standard prenatal vitamin among pregnant women at high risk for gestational diabetes. Explore the effect of increased vitamin D supplementation (4000 IU daily + prenatal vitamin), compared to a standard prenatal vitamin, on glycemic control, need for oral hypoglycemic agents and/or insulin, and delivery outcomes among the subset of women who develop gestational diabetes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
vitamin D supplementation (4000 IU vitamin D3 +prenatal vitamin
University of Minnesota Medical Center
Minneapolis, Minnesota, United States
incidence of gestational diabetes
effect of increased vitamin D supplementation (4000 IU vitamin D3 +prenatal vitamin) on the incidence of gestational diabetes compared to a standard prenatal vitamin among pregnant women at high risk for gestational diabetes.
Time frame: Baseline to Delivery of child
Prescription for insulin or oral hypoglycemic agents
Prescription for insulin or oral hypoglycemic agents
Time frame: Baseline to Delivery of child
Mode of delivery
Natural or C-Section
Time frame: Delivery of child
Birth weight
Weight in Kg
Time frame: Delivery of Child
Apgar score
\<7 at 5 minutes
Time frame: Birth of child to 5 minutes
Shoulder Dystocia
Time frame: Birth of child
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