Procalcitonin Level as a Surrogate for Catheter-related Blood Stream Bacteremia Among Hemodialysis Patients

Benha University28 enrolled

Overview

Hemodialysis patients frequently develop catheter-related blood stream bacteremia (CRBSI). Procalcitonin is a marker of sepsis in bacterial infection. this study for detection of its role as a surrogacy marker in CRBSI.

Catheter-related blood stream bacteremia is common among hemodialysis patients. Clinically, fever and/or rigors with laboratory indicator of inflammation as leucocytosis and elevated c-reactive protein level are considered as markers for CRBSI before blood culture results became available. Procalcitonin is a valid indicator of sepsis. In this study, Procalcitonin level will be measured in any patient with suspected CRBSI and correlation will be tested for proved CRBSI by blood cultures.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Hemodialysis Catheter Infection

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Hemodialysis patients with a dialysis catheter * signs suggestive of CRBSI: fever/chills or leucocytosis with no other site of infection. * Informed consent signed to be enrolled in the study Exclusion Criteria: * Patient with identified cause of fever other than CRBSI

Locations (1)

New jeddah clinic Hospital

Jeddah, Saudi Arabia

Outcomes

Primary Outcomes

Procalcitonin Level

Level of serum procalcitonin

Time frame: 2 minutes after start of fever/chills or other symptoms suggesting CRBSI

Data from ClinicalTrials.gov

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