This is an adaptative study where each participant's rocuronium dose will depend on the previous patient's response, being higher if it was not enough and lower if it was more than enough.
Rocuronium is one of the most used neuromuscular blockers to help intubation and to relax abdominal wall for laparoscopic surgery. Rocuronium intubation dose can be enough for intubation but not last enough for excellent laparoscopic conditions. There is little variation in time from anesthesia induction to the end of the laparoscopy for cholecystectomy and avoiding excess rocuronium dose can help providing excellent conditions and fast track extubation. Dixon's up-and-down method will guide this dose-finding study for the ED50.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
30
intravenous rocuronium infusion
Hospital das Forças armadas
Brasília, Federal District, Brazil
Excellent laparoscopic conditions
Subjective laparoscopic conditions for surgery, assessed by the main surgeon, as excellent or not
Time frame: 30 minutes
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