Enhanced Recovery After Surgery(ERAS) for Gastric Cancer and Perioperative Nutritional Status

The First Hospital of Jilin University1,400 enrolled

Overview

This study is a prospective, single-center, randomized controlled trial. The study protocol was approved by the Ethics Committee at the First Hospital of Jilin University.The perioperation nutritional status will be assessed in gastric cancer patients within ERAS protocols.The ERAS patients were randomly divided into perioperational nutrition support group and conventional pathway group . Inter-group differences were evaluated for nutritional index,clinical recovery index, complications etc.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

SINGLE

Enrollment

1,400

Conditions

Nutrition Disorders

Interventions

perioperational nutrition surpportPROCEDURE

Oral enteral nutrition support（25 kcal/kg or 1.5 g protein/kg） for 3 days before operation

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * A preoperative cancer stage of T2, T3, T4, Any N, M0 without digestive obstruction confirmed by whole body CT scan, which could be treated with laparoscopic gastrectomy; * age 18-75 years; * pathologic confirmation of gastric adenocarcinoma by endoscopic biopsy; * normal hematological, renal, hepatic, and cardiac parameters,American Society of Anesthesiology (ASA) score \< III without severe systemic disease; * no history of treatment with neoadjuvant chemotherapy and/or radiotherapy * PG-SGA score ≥2，\<9 Exclusion Criteria: * patients requiring conversion to open gastrectomy * excessive bleeding (˃ 500 mL);and patients opting out of the study.

Outcomes

Primary Outcomes

complication

fever；wound infection；post-operation bleeding；ileus；stenosis；leakage

Time frame: 30 days after operation

Data from ClinicalTrials.gov

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