Investigation of Non-inferiority of Treatment of Vulvovaginal Dryness With WO2085 Moisturising Cream in Comparison to a Cream With 0.1% Estriol

Inclusion Criteria: * Post-menopausal women with the subjective symptoms of "vulvovaginal dryness" with a sum score (0-16) of the parameters dryness, itching, burning and pain unrelated to sexual intercourse of at least 3 AND a VAS value "Overall impairment of daily life due to the condition "vulvovaginal dryness" \> 0 on Visit 1. * Last menstruation more than 12 months before Visit 1 OR bilateral oophorectomy with or without hysterectomy more than 3 months before Visit 1. * Physical and mental healthy women as assessed by the medical history. * PAP test performed within the last 12 months before Visit 1 and result less than PAP III. * Signed written informed consent before participation in the Trial. * Willingness to actively participate in the trial and to come to the scheduled visits. Exclusion Criteria: * Known hypersensitivity against any of the ingredients of the test products. * Any indication in the medical history regarding an impairment of the hepatic, renal, gastrointestinal, cardiovascular, pulmonary, endocrinological or hematological system (especially venous and arterial thromboembolism, ischemic stroke, myocardial infarction, porphyria) if clinically relevant for this clinical trial (cf. contraindications and warnings for Estriol cream 0.1%). * Known thrombophilic disorders (e.g. protein C, protein S or antithrombin deficiency). * Breast cancer (acute and / or in the medical history or suspected). * Estrogen-dependent tumor (acute and / or in the medical history or suspected, especially ovarian and / or endometrial carcinoma). * Systemic hormonal replacement therapy (tablets, patches, injections, dermal products), or phytohormonal therapy or use of SERMs (inter alia anti-estrogens) within 3 months before Visit 1 and / or during the conduct of this trial. * Intrauterine device (IUD) with progestogen (Mirena®, Jaydess®) * Pathological findings in cancer screening (Papanicolaou III, III D - V in the cervical test) * Pathological changes in the vaginal or cervix area, which are caused by estrogen deficiency (except symptoms and condition of "vulvovaginal dryness"), e.g. diminution of labia caused by estrogen deficiency, constricted introitus. * Patients with known infectious diseases (e.g. hepatitis or HIV infection).