Single center double blind randomised controlled trial. 60 subjects. Giving lidocaine IV or saline to patients due to robot assisted colorectal surgery. Primary outcome is cumulative morphine consumption at 24 hours.
Prospective double blind randomised controlled trial. The investigators are giving lidocaine IV or saline to 60 patients undergoing robot assisted colorectal surgery. Blinding and randomization is done by the hospital pharmacy. Both groups get otherwise the same treatment and a IV PCA (patient controlled administration) morphine pump for objectivisation of opioid consumption. Other outcome measures are NRS (numerical rating score) pain score, PONV (postoperative nausea and vomiting), use of antiemetics and opioid consumption up to 72 hours.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
60
Odense Universitetshospital
Odense, Denmark
Reduction in morphine consumption
PCA morphine added to PN (per necessitae) morphine, cumulated
Time frame: over the first 24 hours
PONV
Postoperative nausea and vomiting - patient is asked
Time frame: up to 72 hours
Reduction in morphine consumption
PCA morphine added to PN morphine, cumulated
Time frame: over the first 72hours
Use of antiemetics postoperative
Time frame: first 72 hours
Time to bowel function
time to flatus or defecation or function of bowel stoma
Time frame: first 72 hours
time to discharge
Time frame: up to 72 hours
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