Acute Effect of Salbutamol on Heart Rate and Blood Pressure During Exercise in Patients With Moderate or Severe Asthma and Healthy Subjects

Inclusion Criteria for asthmatics: * Have the diagnosis of moderate or severe asthma according to the clinical criteria described in the literature * Be between 20 and 59 years of age * Being from the Asthma Assistance and Research Center (NAPA) of University of São Paulo Faculty of Medicine Clinics Hospital * Have treatment at the outpatient clinic for at least 3 months, * Have a stable clinical condition for at least 30 days * Make use of the optimized medicine daily * Read and signed the TCLE approved by the Ethics and Research Committee of the Ibirapuera University (UNIB) under opinion nº 1,574,833 Exclusion Criteria for asthmatics: * Individuals diagnosed with another lung disease, * Have psychiatric, musculoskeletal or cardiovascular diseases, * Being smokers * Being pregnant * Practice regular physical activity. Criterion for inclusion of healthy individuals * Be between 20 and 59 years of age * Healthy individuals * Both genders * Age between 20 and 59 years * Read and signed the TCLE approved by the Ethics and Research Committee of the Ibirapuera University (UNIB) under opinion nº 1,574,833 Criteria for the exclusion of healthy individuals * Pregnant women * Smokers * Psychic diseases * Osteomuscular diseases * Practitioners of regular exercise * Physical Activity Readiness Questionnaire (PAR-Q)