Concentrated Growth Factors Applied in Maxillary Sinus Floor Elevation Via a Lateral Window Approach

Inclusion Criteria: * Loss of one or more maxillary molars in the posterior maxillary region * Occlusogingival distance of \> 4 mm * Residual bone height of 2-5 mm in the posterior maxillary region, no obvious maxillary sinus separation * No problems with the lungs, heart, or brain * Normal liver and kidney function * Normal coagulation function * Adequate prosthetic space * No history of bruxism or temporomandibular joint disorders * No tumors, cysts and polyps in maxillary sinus * No acute or chronic maxillary sinusitis * No acute periodontitis * No oral mucosal disease * Age 20-45 years * Able to tolerate the stress of anesthesia and surgery Exclusion Criteria: * Residual bone height of \< 1 mm in the posterior maxillary region or presence of maxillary sinus mucosa rupture * Poor control of complex periodontal disease * Local inflammation or poor oral hygiene * Poorly treated maxillary disease * With severe bruxism * With temporomandibular joint disorders * Alcohol consumption and cigarette smoking (20 cigarettes/d) * Have a history of chemotherapy and radiation therapy in face and neck * Pregnant * With coagulation disorders * With autoimmune disease * With severe osteoporosis * With acute maxillary sinusitis * Unable to tolerate simple surgery because of systemic diseases including severe diabetes mellitus and heart disease * Unable to provide informed consent