Fixed Combination for Lipid and Blood Pressure Control

Inclusion Criteria: Patients with uncontrolled arterial hypertension (the average 24h blood pressure in the range 130/80 - 180/110 mmHg and / or daytime average blood pressure in the range 135/85-180/110 mmHg) and one of the following: 1. a very high cardiovascular risk and LDL-cholesterol\> 1.8 mmol / l 2. a high cardiovascular risk and LDL-cholesterol\> 2.5 mmol / l 3. Patient with a high or very high cardiovascular risk treated by lipidlowering therapy with statin Exclusion Criteria: 1. hypersensitivity to perindopril or to other ACE inhibitors, amlodipine, atorvastatin, dihydropyridines or to or statins 2. angioneurotic edema in medical history (hereditary / idiopathic or associated with prior treatment with ACE inhibitors) 3. severe hypotension, shock, including cardiogenic shock 4. hemodynamically unstable heart failure 5. Active liver disease or unexplained persistent elevations of serum transaminases more than three times normal 6. Women of childbearing age without reliable contraception 7. pregnancy 8. breastfeeding 9. Patients with contraindications listed in the currently valid SP