This study will evaluate if an association exists between levels of blood flow through the pulmonary veins and the incidence of graft dysfunction post operatively.
Lung transplantation surgery can be fraught with a multitude of early as well as delayed complications leading to increased morbidity and mortality. During lung transplant surgery, trans-esophageal echocardiography (TEE) is routinely used to identify cardiac anatomy and measure blood flow through the pulmonary veins. This blood flow is assessed both before and after the lung has been transplanted. Blood flow through these small caliber vessels can be impacted by many variables with a resulting reduction in blood circulating to the lung, although currently there is no agreement on an acceptable level of flow. This study will look at retrospective data from lung transplant surgeries undertaken at this institution since Jan 1st 2014 until November 18th 2016 with the goal of determining if an association exists between levels of blood flow through the pulmonary veins and the incidence of graft dysfunction post operatively.
Study Type
OBSERVATIONAL
Enrollment
100
No investigational intervention for the purpose of this study was performed; data collected is retrospective data previously collected for non-research purposes.
The Ohio State University Wexner Medical Center
Columbus, Ohio, United States
incidence of graft dysfunction
To describe the relationship between intra-operative pulmonary vein systolic velocities and the incidence of graft dysfunction as defined by the International Society for Heart and Lung Transplantation (ISHLT).
Time frame: at 30 days post-transplant
grade of graft dysfunction
To describe the relationship between intra-operative pulmonary vein systolic velocities and grade of graft dysfunction as defined by the International Society for Heart and Lung Transplantation (ISHLT).
Time frame: at 30 days post-transplant
All-cause mortality
To measure and report all-cause mortality at 30 days post-transplant.
Time frame: at 30 days post-transplant
Hospital Length of Stay
To report subjects hospital length of stay for up to one year.
Time frame: From hospital admission to discharge up to one year.
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