Airflow Perturbation Device (APD) for the Evaluation of Pulmonary and Sleep Disorders

Walter Reed National Military Medical Center199 enrolled

Overview

In a prospective, observational study the investigators compared resistance values measured using the airway perturbation device (APD) to impulse oscillometry and spirometry. The investigators also created reference equations for normal APD resistance ranges using the data from clinically normal volunteers.

Study Type

OBSERVATIONAL

Enrollment

199

Conditions

Airway Obstruction

Interventions

Airflow pertubation deviceDIAGNOSTIC_TEST

Participants have airway resistance measured at the mouth by tidal breathing into a mouth-piece connected to the airflow perturbation device.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Male and female subjects \> 18 years * Referred for PFTs and/or PSG at WRNMMC * All races and ethnicities will be included * Pregnant women will be included Exclusion Criteria: * \< 18 years of age * If mental status is questionable, the patient will be excluded at the discretion of the consenting provider * Unable/unwilling to follow the directions necessary for APD use

Outcomes

Primary Outcomes

Number of participants with APD correlation > 0.5 with spirometry

Respiratory resistance ( cm H20/L/s) measured with APD correlated with volumes (in liters) measured by spirometry.

Time frame: At enrollment

Secondary Outcomes

Number of participants with APD correlation > 0.5 with impulse oscillometry

Respiratory resistance (cm H20/L/s) measured with APD correlated with resistance (cm H20/L/s) measured using impulse oscillometry

Time frame: At enrollment

Data from ClinicalTrials.gov

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