Bicalutamide in Treatment of Androgen Receptor (AR) Positive Metastatic Triple Negative Breast Cancer

Inclusion Criteria: * Age: 18-70 years old, female * Eastern Cooperative Oncology Group (ECOG) 0 or 1 * Confirmed by pathology or organizing cytology AR positive(IHC：≧10%)triple negative breast cancer * For the first time recurrence or newly diagnosed advanced breast cancer,Disease-free survival time 12 months above * Measurable disease per RECIST version 1.1,or immeasurably lesions bone metastasis * After Recurrence has not received cancer treatment * Life expectancy of at least 6 months * Signed and dated an informed consent form Exclusion Criteria: * ECOG score ≧2 * Only brain metastasis or meningeal metastasis * Receiving other anti-tumor treatment * Heart,lung,liver,kidney,bone marrow,and other functions badness