A Prospective, Multi-Center Evaluation of a Powered Vascular Stapler in Video-Assisted Thoracoscopic Lobectomies

Inclusion Criteria: 1. Subjects with a confirmed or suspected diagnosis of stage IA to stage IIB non-small cell lung cancer scheduled for lobectomy (Lung Cancer Staging per American Joint Committee on Cancer,7th Edition)7; 2. Subjects scheduled for VATS lobectomy in accordance with their institution's SOC; 3. Performance status 0-1 (Eastern Cooperative Oncology Group classification); 4. ASA score \< 3; 5. No prior history of VATS or open lung surgery (on the lung in which the procedure will be performed); 6. Willing to give consent and comply with study-related evaluation and treatment schedule; and 7. 18-75 years of age (inclusive). Exclusion Criteria: 1. Active (subject currently receiving systemic treatment) bacterial infection or fungal infection; 2. Systemic administration (intravenous or oral) of steroids, including herbal supplements that contain steroids (within 30 days prior to study procedure); 3. Uncontrolled diabetes mellitus; 4. End stage renal or liver disease; 5. History of severe cardiovascular disease; 6. FEV1% \<50% or severe COPD; 7. Prior chemotherapy or radiation for lung cancer; 8. Scheduled concurrent surgical procedure other than diagnostic wedge resection followed by lobectomy (central venous access - e.g., port placement, mediastinoscopy with lymph node sampling, and VATS lymphadenectomy are allowed); 9. Robotic-assisted procedure; 10. Women who are pregnant or lactating at the time of screening; 11. Physical or psychological condition which would impair study participation; 12. The subject is judged unsuitable for study participation by the Investigator for any other reason; 13. Participation in any other investigational drug (within 30 days or 5 half-lives of an investigational drug) or device study; or 14. Unable or unwilling to attend follow-up visits and examinations.