Trial Comparing Routine Intraoperative Transesophageal Echocardiography During Radical Cystectomy to Standard of Care

University of Chicago80 enrolled

Overview

This is a prospective randomized controlled trial looking at the utility of intraoperative transesophageal echocardiography (TEE) on clinical outcomes after radical cystectomy. Patients in the control group will have standard of care, patients in the TEE group will have standard of care and TEE monitoring throughout. Intraoperative and postoperative variables, such time to extubation, postoperative cardiac and pulmonary complications, intraoperative fluid and vasopressor use will be assessed.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Cardiac and Pulmonary Complications. Central Venous Line Insertion. Gastrointestinal Recovery

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients have elective radical cystectomy at The University of Chicago Hospital. Exclusion Criteria: * Patient refusal, emergent surgery, preoperative mechanical ventilation, preoperative hemodynamic instability (intravenous vasopressor support), and/or esophageal/gastric pathology contraindicating insertion of the transesophageal echocardiography probe.

Outcomes

Primary Outcomes

Incidence of intraoperative central venous line insertion

Time frame: 1 day after study enrollment

postoperative return of bowel function via flatus or passage of stool

Time frame: 5 days after study enrollment

Secondary Outcomes

Decreased postoperative pulmonary and cardiac complications

Time frame: approximately 5-7 days