Ketamine Versus Dexmedetomidine With Local Anesthetic in TAP Block

Assiut University90 enrolled

Overview

Comparing the analgesic effects of ketamine and dexmedetomidine when added to local anesthetic in TAP block for postoperative analgesia after lower abdominal cancer surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Postoperative Analgesia Lower Abdominal Cancer

Interventions

KetamineDRUG

Ketamine at a dose of 0.5mg/kg will be added to bupivacaine 0.25 (total volume 20ml) in each side using sonar guided TAP block

dexmedetomidineDRUG

dexmedetomidine at a dose of 1ug/kg will be added to bupivacaine 0.25 (total volume 20ml) in each side using sonar guided TAP block

control groupDRUG

20ml of 0.25% bupivacaine will be injected in each side of the TAP block

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All patients ASA I and II to whom abdominal surgery for cancer will be conducted will be included in the study Exclusion Criteria: * Coagulopathies * ASA III or IV, patient refusal, sensitivity to the used drugs

Locations (1)

South Egypt Cancer Institute

Asyut, Assiut University, Egypt

Outcomes

Primary Outcomes

postoperative rescue morphine consumption

Time frame: 24 hours postoperative

Data from ClinicalTrials.gov

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