Gestational diabetes mellitus(GDM) is a commom complication during pregnancy and associated with various adverse pregnancy outcomes for both the mother and her offspring. Imoportantly, with the gradual opening of a two-child policy, more and more Chinese women of reproductive age enter pregnancy have a history of GDM. Our previous study showed that regular exercise commenced in early pregnancy is effective in reducing the risk of developing GDM in Chinese overweight and obese pregant women. Thus, in this study, we want to evaluate the effect of lifestyle intervention with detailed information on how to eat and how to diet in preventing the recurrence of GDM.
Gestational diabetes mellitus(GDM) is a commom complication during pregnancy. and the incidence has reached as high as 19.2% in China. GDM is associated with various adverse pregnancy outcomes for both the mother and her offspring, and not only during the perinatal phase, but also in the long term.Thus finding effective way to reduce the risk of GDM is of great importance,especial for women with high GDM risk factors. GDM history is one of the risk factors. Imoportantly, with the gradual opening of a two-child policy, more and more Chinese women of reproductive age enter pregnancy have a history of GDM. Our previous study showed that regular exercise commenced in early pregnancy is effective in reducing the risk of developing GDM in Chinese overweight and obese pregant women. Thus, in this study, we want to evaluate the effect of lifestyle intervention with detailed information on how to eat and how to diet in preventing the recurrence of GDM
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
660
With the dietary intervention we aimed to promote a healthy pattern of eating but not necessarily to restrict energy intake.For example we suggested exchanging carbohydrate-rich foods with a medium-to-high glycaemic index for those with a lower glycaemic index to reduce the glycaemic load, and restricting dietary intake of saturated fat. With respect to advice on physical activity, we focused on incremental increases in walking from a pedometer assessed, or encourage them to do moderate cycling during pregnancy.
Peking University First Hospital
Beijing, Beijing Municipality, China
RECRUITINGGDM
According to the new criteria amended in August 2014 in China, GDM was diagnosed when any one value reaches or exceeds 5.1 mmol/L at 0 hours, 10.0 mmol/L at 1 hour, or 8.5 mmol/L at 2 hours. Values of 7.0 mmol/L at 0 hours or 11.1 mmol/L at 2 hours were diagnosed as DM, regardless of the pregnancy stage
Time frame: 24-28 gestational weeks
birth weight
birth weight measured after baby was delivered and accurate to 0.1 kg
Time frame: up to 43 gestational weeks
gestational weeks
record the gestational weeks for delivery
Time frame: up to 43 gestational weeks
delivery mode
this includes vaginal delivery, operative vaginal delivery or cesarean delivery
Time frame: up to 43 gestational weeks
macrosomia
birth weight above 4000.0 g
Time frame: up to 43 gestational weeks
LGA
birth weight above the 90th percentile for gestational age
Time frame: up to 43 gestational weeks
SGA
birth weight below the 10th percentile for gestational age
Time frame: up to 43 gestational weeks
gestational hypertention
defined as blood pressure elevation \[systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg\] after 20 weeks gestation in the absence of proteinuria
Time frame: up to 43 gestational weeks
pre-eclampsia
defined as new-onset hypertension \[systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg\] and new-onset proteinuria \[300 mg of protein in 24 hours or a urine protein/creatinine ratio of 0.3 mg/dL\] after 20 weeks gestation or, in the absence of proteinuria, new-onset hypertension with new-onset thrombocytopenia, renal insufficiency, impaired liver function, pulmonary edema, or cerebral or visual disturbances
Time frame: up to 43 gestational weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.