Perioperative Hypogonadism in Men Undergoing Radical Cystoprostatectomy for Bladder Cancer

University of Kansas Medical Center25 enrolled

Overview

The purpose of this study is to examine the relationship between testosterone level changes around the time of radical cystectomy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Bladder Cancer Low Testosterone Levels

Eligibility

Sex: MALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis of bladder cancer * Scheduled to undergo radical cystectomy Exclusion Criteria: * Evidence of advanced metastatic disease, * Undergoing cystectomy for non-bladder primary malignancy or bladder cancer type other than urothelial cell * History of breast or prostate cancer * Polycythemia, cardiovascular thromboembolism, untreated obstructive sleep apnea, uncontrolled heart failure, or acute coronary event in the past six months

Locations (1)

University of Kansas Medical Center

Kansas City, Kansas, United States

Outcomes

Primary Outcomes

Number of Hypogonadism in Participants Based on Serum Testosterone 90 Days Post Radical

The count of participants with hypogonadism (the level of serum testosterone used as a threshold).

Time frame: 90 days post-RC surgery

Secondary Outcomes

The Number of Hypogonadism in Participants Based on Serum Testosterone 30 Days Post Radical Cystectomy

The count of participants with hypogonadism 30 days post radical cystectomy using the serum testosterone levels (the level of serum testosterone used as a threshold).

Time frame: 30 days post-RC surgery

The Number of Hypogonadism in Participants Based on Serum Testosterone Immediately Post Surgery Days Post Radical Cystectomy

The count of participants with hypogonadism immediately post radical cystectomy based on levels of testosterone (the level of serum testosterone used as a threshold).

Time frame: Immediately post-operatively RC surgery

The Number of Hypogonadism in Participants Based on Serum Testosterone at Baseline Days Post Radical Cystectomy

The count of participants with hypogonadism at baseline days post radical cystectomy (the level of serum testosterone used as a threshold).

Time frame: Baseline, prior to RC surgery

Data from ClinicalTrials.gov

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