The purpose of this study is to improve health professionals understanding of preterm infant growth patterns, and to determine if early growth patterns predict risks of adverse metabolic and cognitive outcomes.
The purpose of this study is: To improve health professionals understanding of preterm infant growth patterns, and to determine if growth patterns (rapid early growth in the first 2 weeks of life, weight less than the 10th percentile at the time of discharge) predict risks of adverse metabolic outcomes (measured as overweight at age 3) once the following variables are controlled for: size at birth (z-score), neonatal morbidities, social determinants of health, and nutritional adequacy in the neonatal intensive care unit (NICU). To assess diagnostic accuracy of 36-week anthropometric weight, length and head circumference \<10th and \<3rd percentiles to predict preterm infant cognitive impairment.
Study Type
OBSERVATIONAL
Enrollment
1,275
Some preterm infants grow at higher rates than others
Cumming School of Medicine
Calgary, Alberta, Canada
Regina Qu'Appelle Health Region
Regina, Saskatchewan, Canada
Neurodevelopment
Neurodevelopment (Bayley scale scores II and III), diagnoses of cerebral palsy, or other neurologic impairments) measured
Time frame: Twenty-one months of age
Overweight
Overweight will be defined as body mass index
Time frame: Three years of age
Growth patterns
Growth patterns of preterm infants relative to the Fenton growth chart
Time frame: From birth to 50 weeks post-menstrual age
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