Whole-Heart Myocardial Blood Flow Quantification Using MRI

Inclusion Criteria: * 60 healthy male or female (18 or older) participants * 110 male or female adults (18 or older) who have undergone clinical myocardial perfusion imaging at CSMC and been diagnosed with Coronary Disease (CAD). * 50 female adults (21 or older) who have undergone coronary reactivity testing at CSMC and been diagnosed with coronary microvascular disease (CMD). Exclusion Criteria: * MR imaging is contraindicated in persons with mechanically, magnetically, or electrically activated implants, such as cardiac pacemakers, neurostimulators, and infusion pumps. * Persons with ferromagnetic implants and ferromagnetic foreign bodies, such as intracranial, aneurysm clips, shrapnel and intraocular metal chips as these could become dislodged. * Patients who are pregnant, nursing, implanted with non MR-compatible intrauterine devices (IUD's) * Persons unable to tolerate MRI imaging secondary to an inability to lie supine or severe claustrophobia. * Persons who are non-compliant with visit instructions, including inability to lie still, hold breath or follow procedure instructions * Persons whose renal function test does not meet CSMC standard of care MRI contrast protocol requirements (GFR \<45ml/min). * Persons with stated allergy to animal dander * acute coronary syndrome or acute myocardial infarction or ongoing myocardial ischemia or ECG evidence of ongoing ischemia; * patients with concurrent cardiogenic shock or requiring inotropic or intra-aortic balloon support or prior/planned PCI or CABG; * non-ischemic cardiomyopathy or more than moderate valvular disease; * contraindication to stress agent (adenosine) including asthma or prior adverse reaction to adenosine * contraindications for gadolinium contrast;