This study is designed as a randomized, single blind (data evaluation), placebo controlled, full cross-over study and conducted in 166 (including 10% drop out) males and females, aged ≥ 18 and ≤ 65 and waist circumference of \>80 cm for women and \>94 cm for men (indicating increased risk of metabolic complications (WHO)) and having a sedentary lifestyle. Subjects will receive rice with a tea extract and rice without a tea extract. There will be three visits to the test facility: one screening visit and two intervention visits. During the intervention visits venous blood samples will be collected for the analysis of plasma glucose (t = -30m, -5m, 15m, 30m, 45m, 1h, 1h 30m, 2h and 3h, relative to the start of rice consumption ) and serum insulin (t = -5m, 30m, 1h, 2h and 3h). Between the two intervention visits subjects have an interval of one week. This interval is required to minimize subject discomfort from repeated blood sampling.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
166
Rice with tea extract
Rice without tea extract
Atlantia Food Clinical Trials
Cork, Ireland
Incremental area under the plasma glucose versus time curve
Time frame: 0-2 hours
Incremental area under the plasma glucose versus time curve
Time frame: 0-3 hours
Maximum venous glucose concentration
Time frame: 0-3 hours
Total area under the post prandial insulin versus time curves
Time frame: 0-2 hours
Total area under the post prandial insulin versus time curves
Time frame: 0-3 hours
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