Islet quality control after pancreatic islets isolation process is insufficient. The Islet Chip study proposes to develop a bio-sensor that will allow a multi-parametric analysis of islet graft based on measurement of islet membrane electric potential.
Islet quality control after pancreatic islets isolation process is insufficient. The Islet Chip study proposes to develop a bio-sensor that will allow a multi-parametric analysis of islet graft based on measurement of islet membrane electric potential. The project aims to : * develop the bio-sensor necessary to measure islet membrane electric potential * develop interface between bio-sensor and user * correlate analysis data collected by bio-sensor with metabolic results of islet graft
Study Type
OBSERVATIONAL
Enrollment
40
Besançon University Hospital
Besançon, France
RECRUITINGClermont Ferrand University hospital
Clermont-Ferrand, France
NOT_YET_RECRUITINGGrenoble University Hospital
Grenoble, France
Beta-score
Beta-score in continuous variable, using the last Beta-score known before the second islet graft. Beta-score is a composite score that reflects pancreatic islet graft function after transplantation and measured from the following criteria: severe hypoglycemia, HbA1c, stimulated C-peptide, fasting glucose, insulin dose or oral diabetes, glycemic variability.
Time frame: 6 months in average before second islet graft
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Lyon University Hospital
Lyon, France
RECRUITINGMontpellier University Hospital
Montpellier, France
RECRUITINGNancy University hospital
Nancy, France
NOT_YET_RECRUITINGUniversity hospital of Strasbourg
Strasbourg, France
RECRUITINGGeneva University Hospital
Geneva, Switzerland
ACTIVE_NOT_RECRUITING