The purpose of this study is to determine whether microwave ablation is more effective in the treatment of simple renal cysts than conventional laparoscopic decortication.
Background: Simple renal cysts are the most common renal masses, and occur in half of all patients older than 50 years.They are usually asymptomatic and benign, asymptomatic and discovered incidentally. However, over time, these simple cysts can enlarge, become symptomatic and develop complications, requiring intervention.They can be managed by a variety of surgical and percutaneous methods, including percutaneous aspiration (with or without injection of a sclerosing agent), endoscopic marsupialization or excision, open surgery and laparoscopic cyst excision.Percutaneous aspiration and sclerotherapy have been described as safe and effective methods of managing symptomatic simple renal cysts without the cost and morbidity associated with conventional surgery and laparoscopy.However, laparoscopic decortications and simple aspiration is associated with a high recurrence rate because the cyst wall epithelium is responsible for active liquid production. Purpose:To determine whether microwave ablation is more effective in the treatment of simple renal cysts than conventional laparoscopic decortication. Method:
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
300
KY2000 microwave ablation system was used in the experimental group. A power output of 60 W for 1-3 min for 1-3 cycles to treat the renal cysts according to the cysts size and classification.Percutaneous microwave ablation will be performed under the guidance of ultrasound while the laparoscopic microwave ablation will be performed under direct vision
conventional laparoscopic decortication will be performed to treat the renal cysts
Yonghui Chen
Shanghai, Shanghai Municipality, China
RECRUITINGlocal recurrence
Time frame: 12 months postoperatively
postoperative complications
Time frame: postoperative,up to 30 days
operative time
Time frame: during operation
Hospital stay time
Time frame: time from the date of admission until the date of discharge, up to 2 weeks
quality of life assessed by quality of life questionnaire
Time frame: postoperative,up to 6 months
change from baseline glomerular filtration rate (GFR) of the affected kidney, 12 months minus baseline
Time frame: baseline and 12 months
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