149 HBV carriers with inadequate serum vitamin D levels were randomized to two groups: one is supplied with vitamin D and another without as controls. The markers of HBV replication were compared before and after treatment.
This is a randomized case-control trial. A total of 149 HBV carriers with inadequate vitamin D (\< 30 ng/mL) level were enrolled. They were randomly divided to two groups: one group receiving vitamin D supplement (1600 IU/day) for 2 months and another group as controls. The serum vitamin D, HBV DNA and qHBsAg levels were measured at baseline and after vitamin D supplement. Whether HBV DNA and qHBsAg have significant change after vitamin D supplement can be determined.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Enrollment
149
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
New Taipei City, Taiwan
The Dynamic Change of HBV DNA
the serum HBV DNA levels were measured in CH-B patients before and after 2-month vitamin D supplement
Time frame: baseline, after 2-month vitamin D supplement
The Change of Serum qHBsAg (IU/mL)
The serum qHBsAg levels were measured before and after 2-month vitamin D supplement
Time frame: baseline, after 2-month vitamin D supplement
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