The investigators designed a prospective study in this article to evaluate the efficacy, the life quality and the complications of two different meshes of type I (one is Perigee/Apogee, the other is named Gynecare prolift) versus traditional surgery, and also studied the influence of some surgical procedures on the prognosis.
Pelvic organ prolapse is defined as a downward descent of the pelvic organs that results in the protrusion of vagina, uterus, or both. The investigators designed a prospective study in this article to evaluate the efficacy, the life quality and the complications of two different meshes of type I (one is Perigee/Apogee, the other is named Gynecare prolift) versus traditional surgery. The investigators also studied the influence of some surgical procedures on the prognosis. In this study,The investigators divided the patients randomly into three groups :the group A was a total of 91 patients who accepted transvaginal hysterectomy and total pelvic floor reconstruction combined Perigee and Apogee polypropylene mesh(PA);the group B was a total of 97 patients who accepted transvaginal hysterectomy and total pelvic floor reconstruction with Gynecare prolift polypropylene mesh;the group C was a total of 70 patients who accepted transvaginal hysterectomy and anterior and posterior vaginal wall repair without any mesh.The investigators did POP-Q measurements and questionnaire preoperatively and postoperatively and recorded volume of bleeding,day of postoperative indwelling catheter and the mesh complications。
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DEVICE_FEASIBILITY
Masking
DOUBLE
Enrollment
258
The investigators divided the patients randomly into three groups :the group A received Perigee and Apogee polypropylene mesh(PA);the group B received Gynecare prolift polypropylene mesh;the group C was without any mesh.
The investigators divided the patients randomly into three groups :the group A received Perigee and Apogee polypropylene mesh(PA);the group B received Gynecare prolift polypropylene mesh;the group C was without any mesh.
The investigators divided the patients randomly into three groups :the group A received Perigee and Apogee polypropylene mesh(PA);the group B received Gynecare prolift polypropylene mesh;the group C was without any mesh.
Pelvic Organ Prolapse Quantification
the prolapse of stage II and above is defined as recurrence in POP-Q stage.
Time frame: at 12 months after surgery
sexual quality of life through the pelvic organ prolapse / urinary incontinence sexual questionnaire
PISQ-12
Time frame: at 12 months after surgery
pelvic floor distress inventory short form
PFDI-20
Time frame: at 12 months after surgery
mesh exposure
mesh was seen in the vagina by gynecological examination
Time frame: at 12 months after surgery
sexual quality of life through the pelvic organ prolapse / urinary incontinence sexual questionnaire
PISQ-12
Time frame: at 24 months after surgery
Pelvic Organ Prolapse Quantification
the prolapse of stage II and above is defined as recurrence in POP-Q stage.
Time frame: at 24 months after surgery
pelvic floor distress inventory short form
PFDI-20
Time frame: at 24 months after surgery
mesh exposure
mesh was seen in the vagina by gynecological examination
Time frame: at 24 months after surgery
sexual quality of life through the pelvic organ prolapse / urinary incontinence sexual questionnaire
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PISQ-12
Time frame: baseline
pelvic floor distress inventory short form
PFDI-20
Time frame: baseline
stress urinary incontinence
leakage of urine with exertion or with sneezing or coughing
Time frame: at 1 months after surgery
stress urinary incontinence
leakage of urine with exertion or with sneezing or coughing
Time frame: 3 months after surgery
Volume of bleeding
Time frame: during the operation
Elevated blood pressure
Time frame: during the operation
Day of postoperative indwelling catheter
Time frame: 1 months after surgery
Number of constipation
Time frame: 1 months after surgery