The aim of the present study is to test a hypothesis assuming that phototherapy might have an effect on oxidant/antioxidant status in term and late-preterm neonates with unconjugated hyperbilirubinemia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
120
estimate oxidative stress and trace elements in neonates with unconjugated hyperbilirubinemia after exposure to phototherapy
Effect of types of phototherapy on change in total antioxidant capacity (TAC)
This will be determined by: 1. Measure TAC (mmol/L) before and after phototherapy 2. Compare results of TAC (mmol/L) before and after phototherapy.
Time frame: 2 days
Effect of types of phototherapy on change in malonaldehyde (MDA)
This will be determined by: 1. Measure MDA (nmol/L) before and after phototherapy 2. Compare results of MDA (nmol/L) before and after phototherapy.
Time frame: 2 days
Effect of types of phototherapy on change in nitric oxide (NO)
This will be determined by: 1. Measure NO (umol/L) before and after phototherapy 2. Compare results of NO (umol/L) before and after phototherapy.
Time frame: 2 days
Effect of types of phototherapy on change in serum iron (Fe)
This will be determined by: 1. Measure serum Fe before and after phototherapy 2. Compare results of serum Fe before and after phototherapy.
Time frame: 2 days
Effect of types of phototherapy on change in serum copper (Cu)
This will be determined by: 1. Measure serum Cu before and after phototherapy 2. Compare results of serum Cu before and after phototherapy.
Time frame: 2 days
Effect of types of phototherapy on change in serum zinc (Zn)
This will be determined by: 1. Measure serum Zn before and after phototherapy 2. Compare results of serum Zn before and after phototherapy.
Time frame: 2 days
Effect of types of phototherapy on change in serum calcium (Zn)
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This will be determined by: 1. Measure serum Ca before and after phototherapy 2. Compare results of serum Ca before and after phototherapy.
Time frame: 2 days