Insecticide Resistance Management in Burkina Faso and Côte D'Ivoire

Institut de Recherche pour le Developpement15,776 enrolled

Overview

This study evaluates the benefit to use 1) insecticide residual sprayings, 2) larvicides, 3) Ivermectin for domestic animals and 4) behaviour change communication strategy to complement the universal coverage with LLINs through a cluster randomized trial.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

15,776

Conditions

Malaria

Interventions

Indoor residual sprayingsDEVICE

Houses will be spayed with this formulation containing Pyrimiphos methyl.

LarvicideDEVICE

Larval breeding sites will be treated with larvicide

BCCBEHAVIORAL

Ivermectin

Eligibility

Sex: ALLMax age: 21 YearsHealthy volunteers:

Medical Language ↔ Plain English

For Cross-sectional surveys only, maximum age for participating in the study was 21 y/o in Côte d Ivoire and 18 y/o in Burkina Faso.

Locations (2)

Institut de Recherche en Sciences de la Santé

Bobo-Dioulasso, Burkina Faso

Institut Pierre Richet

Bouaké, Côte d’Ivoire

Outcomes

Primary Outcomes

Malaria incidence density

Malaria cases (whole population, every ages) registered in the local health system.

Time frame: continuous monitoring during 2 years

Secondary Outcomes

Entomological Inoculation Rate

Number of infectious bites/personn

Time frame: Every 8 weeks during 2 years

Malaria prevalence

% of positive blood smears among the 0-18 y/o population as recorded during cross sectional surveys.

Time frame: Every 4 months during 2 years

Data from ClinicalTrials.gov

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