Pre-ERCP High Carbohydrate Drinks Improve Patients Recovery

Hepatopancreatobiliary Surgery Institute of Gansu Province1,292 enrolled

Overview

To test the benefits of extra high carbohydrate liquid diet uptake 2 hours before ERCP in improving patients' early recovery.

Enhanced recovery after surgery (ERAS) has been formed of procedure which contains preoperative education, improvement of anesthesia, reducing the number of drainage tubes, and early diet after surgery. In recent years, because of its positive advantages, ERAS was widely accepted in surgical fields. For upper gastrointestinal surgery, high-carbohydrate drinks can be given 2 hours before surgery in order to guarantee the stability of blood glucose and circulation during the operation. It obviously reduce the preoperative thirst, hunger, irritability and even the incidence of postoperative complications. However ERAS program is rarely studied in ERCP. Theoretically we can use ERAS as a strategy to reduce post-ERCP uncomfortable and complications.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

1,292

Conditions

Complication

Interventions

400ml high carbohydrate liquid diet before ERCPPROCEDURE

400ml high carbohydrate liquid diet uptake 2 hours before ERCP

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ERCP patients, * Age 18-85 years old. Exclusion Criteria: * Coagulation dysfunction (INR\> 1.3) and low peripheral blood platelet count(\<50×109 / L) or using anti-coagulation drugs, * Preoperative coexistent diseases: acute pancreatitis, GI tract hemorrhage, severe liver disease, shock, liver or kidney malfunction, * Diabetes（blood glucose fluctuations）or with complications, * Intestinal obstruction or other contraindications with feeding and watering, * Prior surgery of Bismuth Ⅱ and Roux-en-Y, * Pregnant women, * Unwillingness or inability to consent for the study.

Locations (15)

Third Military Medical University

Chongqing, Chongqing Municipality, China

The first hospital of Lanzhou university

Lanzhou, Gansu, China

Outcomes

Primary Outcomes

Levels of fatigue (Fatigue Scale-14 scoring system)

The patients always feel tired and faint. The clinical manifestation includes slow to respond, the flexibility and coordination disorders.

Time frame: 6 months

Abdominal pain

Pain score (scores:1-10)

Time frame: 6 months

Secondary Outcomes

The average incubation time

The time of total procedure

Time frame: 6 months

Successful cannulation time

From first achieve the papilla to success cannulation

Time frame: 6 months

Postoperative abdominal distention

Distention uncomfortable

Time frame: 6 months

Postoperative nausea and vomiting

Nausea or vomiting after procedure

Time frame: 6 months

Complications

Pancreatitis, cholangitis, bleeding, aspiration, et,al.

Time frame: 6 months

Blood glucose

Intra-operative blood glucose and 2 hours' blood glucose after procedure

Time frame: 6 months

Intraoperative residues in stomach

The volume of stomach residues

Data from ClinicalTrials.gov

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