Epipage 2 (epidemiologic study on small-for-gestational-age children) is a nationwide study implemented to improve our knowledge of the outcome of preterm children in France. This study was launched on March 28, 2011 and includes three groups of preterm children, all born before 35 weeks: extremely preterm infants (born between 22 and 26 completed weeks of gestation), very preterm children (born between 27 and 31 completed weeks) and moderately preterm children (born between 32 and 34 completed weeks). These children are being studied from their birth up to the age of 12 years. At birth, data on maternal and infants' characteristics were collected from medical records. At one and two years, questionnaires sent to families and to physicians (at two years only) allowed to collect data about the children's life and health. At five and a half years, medical and psychological assessments are specifically implemented for the study in order to evaluate motor and cognitive disorders in this population.
Study Type
OBSERVATIONAL
Enrollment
3,404
Assessment of health status and development will be performed in specific centers at 5 and a half years. This check-up includes a complete medical examination to look for visual, hearing, motor impairment and health problems, and psychological tests using standardized tools (WPPSI IV ((Wechsler Preschool and Primary Scales Intelligence)) and NEPSY 2 tests) to assess cognitive development of very preterm children. A parental questionnaire will be fulfilled to investigate family's social conditions, maternal health, autism spectrum disorders (Social Communication Questionnaire), the child's quality of life and behavioral development (Strengths and Difficulties Questionnaire).
Centre Hopsitalier d'Agen
Agen, France
CAMSP Albi
Albi, France
CHU Amiens
Amiens, France
CHU d'Angers
Angers, France
CH d'Arras
Arras, France
CAMSP Auch
Auch, France
Health disorders assessed by medical exam
According to gestational age at birth
Time frame: 5 years 5 months- 5 years 11 months
Motor disorders assessed by medical exam
According to gestational age at birth
Time frame: 5 years 5 months- 5 years 11 months
Cognitive disorders assessed by psychological testing
According to gestational age at birth
Time frame: 5 years 5 months- 5 years 11 months
Behavioural disorders by psychological testing
According to gestational age at birth
Time frame: 5 years 5 months- 5 years 11 months
Changes in medical practices collected by questionnaire
Time frame: 5 years 5 months- 5 years 11 months
Changes in organization of care collected by questionnaire
Time frame: 5 years 5 months- 5 years 11 months
Set up a DNA Biobank by saliva samples collection
Time frame: 5 years 5 months- 5 years 11 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Centre Hospitalier Côte Basque
Bayonne, France
CH Beauvais
Beauvais, France
CHU Jean Minjoz
Besançon, France
Centre Hospitalier de Bordeaux
Bordeaux, France
...and 88 more locations