The study evaluates the efficacy of local anesthestic application through the catheter in the surgical wound for the postoperative pain relief after minimally invasive aortic valve surgery. The patients will be enrolled in two different groups according to the protocol of the local anesthetic and saline administration: 1. group: continous infusion of the local anesthetic plus bolus on demand 2. group: continous infusion of saline plus bolus on demand For all patients metamizol every 12 hours plus bolous of piritramid on demand.
Patients undergoing minimally invasive aortic valve replacment surgery will be enroled in the study, after giving a signed informed consent. The study evaluates the efficacy of local anesthestic application through the catheter in the surgical wound for the postoperative pain relief after minimally invasive aortic valve surgery. Patients will then be randomised in two groups according to the protocol: 1. group: continous infusion of the local anesthetic plus bolus on demand 2. group: continous infusion of saline plus bolus on demand All patients will receive Metamizol every 12 hours plus bolus of piritramid on demand. Analgesia effectivness will be checked hourly according to the visual analogue scale (VAS). According to protocol, bolus will be given every time the score of VAS scale is \>3. The catheter will be removed 48 hours after the protocols' start.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
76
Piritramid will be administered i.v., if the patients feel pain after receiving a bolus of Ropivacaine or saline through the catheter.
Piritramid will be administered i.v., if the patients feel pain after receiving a bolus of Ropivacaine or saline through the catheter.
University Clinical Center Ljubljana
Ljubljana, Slovenia
Comparison of cumulative postoperative dose of Piritramid between the two different protocols, using VAS scale to determine level of analgesia.
Comparison of cumulative postoperative dose of Piritramid between the two protocols
Time frame: 48 hours after admission to the intensive care unit (ICU)
Complications related to the catheter in the surgical wound
Complications related to the catheter in the surgical wound
Time frame: Up to 30 days
Visual analogue scale (VAS), frequency of scores higher than 3
Visual analogue scale (VAS), frequency of scores higher than 3
Time frame: 48 hours after admission to the ICU
Patients satisfaction with pain relief measured by Likert-type Patient satisfaction scale
Patients satisfaction regarding pain relief, in the following order 1.very satisfied 2.satisfied 3.neither satisfied nor dissatisfied 4.dissatisfied 5.completely dissatisfied
Time frame: 72 hours after surgery
Rate of complications related to the local anesthetic
Neurotoxicity and cardiotoxicity related to the local anesthetic
Time frame: 72 hours after surgery
Hospital lenght of stay
Hospital lenght of stay
Time frame: Up to 30 days
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