The purpose of this research study is to help determine whether practicing resisting the urge to smoke changes brain function or behavior among smokers.
The study is comprised of two parts: a pilot to test procedures to be used in the study, followed by the study. The pilot phase of this study will enroll 30 participants. The main study will enroll 80 after the pilot phase is completed. The pilot phase includes all of the same procedures as the main study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
79
Participants asked to delay time until they smoke first cigarette of the day.
Participants receive tips on how to resist the urge to smoke and control cravings to smoke.
Hoglund Brain Imaging Center, University of Kansas Medical Center
Kansas City, Kansas, United States
Increase in percent blood oxygenation level dependent (BOLD) signal change in cognitive control network in response to smoking versus nonsmoking cues
Change measured via functional magnetic resonance imaging (fMRI)
Time frame: Baseline (Day 7) to End of Study (Day 22)
Decrease in percent (BOLD) signal change in reward network in response to smoking versus nonsmoking cues
Change measured via functional magnetic resonance imaging (fMRI)
Time frame: Baseline (Day 7) to End of Study (Day 22)
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