This study evaluates the possible beneficial effect of fat grafting for post mastectomy pain syndrome. Half of patients will receive fat grafting and the other half of patients will receive sham.
Several studies have suggested that fat grafting can alleviate pain in post mastectomy pain syndrome. These studies however have either been in the form of case series or unblinded studies with great risk of bias. It is believed that fat grafting with its content of adipose-derived stem cells can modulate the scar tissue upon grafting and hereby decrease pain. In this study patients will be randomized to either fat grafting or a sham procedure where they undergo the same liposuction but no fat grafting, only injection of saline instead of fat.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
40
Liposuction is performed on the abdomen or thighs as determined before randomization by the surgeon.
The harvested lipoaspirate is injected at the site of pain.
Saline will be injected at the site of pain instead of fat
Odense University Hospital
Odense, Denmark
Pain on visual analog scale (VAS) 0-10
Pain on visual analog scale (VAS) 0-10
Time frame: 6 months
Neuropathic Pain Symptom Inventory
Questionnaire
Time frame: 3 and 6 months
Use of pain medication
pain medication used is registered on questionnaire
Time frame: 3 and 6 months
Pain on visual analog scale (VAS) 0-10
Pain on visual analog scale (VAS) 0-10
Time frame: 3 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.