HPV infections may be responsible for different types of cancer in females. Primary Goal of the study was to identify the prevalence of an hpv affiliation in retrospective-prospective analysed cohort of patients who suffer from vulvar cancer and their preinvasive lesions.
HPV infections may be responsible for different types of cancer in females. Primary Goal of the study was to identify the prevalence of an hpv affiliation in retrospective-prospective analysed cohort of patients who suffer from vulvar cancer and their preinvasive lesions. After having retrospectively identified patients with vulvar cancer incl. their preinvasive lesions in the clinical registry the hpv status of the samples is prospectively analyzed using a new multiplex pcr Array. Two Groups are build: patients with hpv associated vulvar cancer and patients with non-hpv associated vulvar cancer. Then, the rate of patients who respond to radiotherapy within the Groups is analyzed by building Kaplan meier plots according to the patients survival and recurrence rate.
Study Type
OBSERVATIONAL
Enrollment
110
PCR is performed with all patients. The result (hpv positive or negative) will define the patiens Group Affiliation.
Luebeck University, Department for obstetrics and gynecology
Lübeck, Schleswig-Holstein, Germany
prevalence of hpv infections among pations suffering from vulvar cancer and preinvasive lesions
Time frame: 15yrs
disease free survival among the groups
Time frame: 15yrs
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