This study compared the efficiency of pulp revascularization and MTA apexification in the treatment of patients with necrotic immature anterior teeth.
the participants with 66 anterior necrotic immature teeth were randomly assigned into two equal groups with 33 teeth per each, according to regeneration and MTA apexification. At the first visit, all teeth were accessed and irrigated with NaOCl then a TAP was applied as intra-appointment intracanal medication. At the second visit, after removal of the medication with the irrigation, bleeding was initiated into the canal and isolated by the MTA in the orifice in the regeneration group. While in the Apexification group, the MTA was packed apically and all teeth were finally restored with resin composite restorations. The patients were recalled after 1, 3, 6, and 9 months for clinical and radiographic follow up.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
66
a sterile sharp needle was used to irritate the apical tissue until bleeding occurred apically in the root canal space so as to create a biological scaffold for the regenerative process
a 3-5 mm thickness of MTA using a hand plugger and was verified radiographically.
Pain intensity measures
self reported pain intesity at 4, 12, 24, and 48 hours.(0= no pain and 100=worst pain) with a scale from 0 to 100 after the two visits.
Time frame: 2 days
Resolution of periapical pathosis
Radiographically: by comparing radiolucencies in 9 months postoperative radiograph to the baseline radiograph.
Time frame: 9 months
Amount of radiographic increase in root length:
Root length was measured as a straight line from the cement-enamel junction to the radiographic apex of the tooth in millimeters = (9months follow up length - baseline length)
Time frame: baseline and 9 months
Amount of radiographic increase in the root dentinal wall thickness:
Dentin thickness was measured by =root thickness-pulp space and compared to the baseline radiograph measurements.
Time frame: baseline and 9 months
Decrease of apical diameter:
the diameter of the apical foramen was measured in millimeters and compared to the baseline radiograph measurements
Time frame: baseline and 9 months
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