Traditionally, video-assisted thoracic surgery is performed under general anesthesia with double-lumen endotracheal tube. However, the complications associated with this large tube as well as inhalation anesthetics are frequently reported. Therefore, currently there is a trend toward non-intubated anesthesia methods for video-assisted thoracic surgery, which includes thoracic epidural block, peripheral nerve block, local anesthesia, local combined with peripheral nerve block, etc. Thoracic epidural block demands a high technique, but still risks catastrophic neurological complications in case of accidental dural puncture. Local anesthesia, perhaps more straightforward, however may need supplemental analgesia during incision, which will inevitably interrupt surgery and negatively affect the patients. This study aims to apply ultrasound guidance during local anesthetic injection for local anesthesia-based video assisted thoracic surgery, which helps inject the local anesthetic into the key intercostal nerve plane to provide more specific and precise blockade, thus avoiding the chance of blind injection. At the same time, ultrasound guidance has the potential to reduce the risk of systemic toxicity, prolong the duration of analgesia postoperatively, and facilitates postoperative recovery.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
30
VATS is the abbreviation of video-assisted thoracic surgery, which aims to minimize the wound for thoracic surgery and to enhance patient recovery after surgery
30 mL 0.5% ropivacaine is used to achieve VATS block
1:400000 epinephrine is mixed with ropivacaine (local anesthetic) to reduce the risk of local anesthetic systemic toxicity
Numerical rating scale intraoperatively
Self-reporting pain intensity, pain site, and analgesic dosage during surgery
Time frame: During chest wall incision
TIme to lose skin sensation (light touch and thermal) over the injection site
Skin sensation will be tested every 5 minutes after ropivacaine injection until loss of both sensation (readiness for skin incision)
Time frame: Up to 30 mins after ropivacaine injection
Ropivacaine concentration at different time points after injection
Blood sampling at seven time points (10, 20, 30, 45, 60, 90, 120 minutes following injection)
Time frame: Up to 120 mins following injection
Common characteristics of ultrasound anatomy by analyzing video clips
Recording the ultrasound images at three time points
Time frame: Three time points (upon obtaining informed consent, prior to injection and during injection)
Numerical rating scale postoperatively
Pain scores evaluated at six time points (at the conclusion of surgery, and at 2h, 6h, 24h, 48h, and 72h post-surgery)
Time frame: Up to 72 hours following surgery
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