Neuromuscular electrical stimulation (NMES) implemented during the intensive care unit(ICU) stay may improve exercise capacity and prevent muscular weakness in critically ill patients with respiratory disease. Main objective: To evaluate, in respiratory critically ill patients, the effects of a conventional physiotherapy program with or without additional NMES applied only during the ICU stay on exercise capacity. Design: Randomized, controlled, double-blind clinical trial on patients (\>18yo) with diagnosis on admission of acute or acute on chronic respiratory disease, on mechanical ventilation (MV) \> 72h and expected MV \> 24h. Intervention: Conventional physiotherapy with or without 30-minutes (5days/week) on quadriceps femoris and gluteus maximus. Patients in the control group will follow the same protocol but the device will not be activated. Measures: Demographic data, body composition through bioelectrical impedance analysis (BIA), and functional capacity before admission through Barthel scale will be registered upon inclusion. Exercise capacity through test sit-to stand, muscular strength through Medical Research Council (MRC) score and dynamometry, body composition through BIA, and functional capacity through Barthel scale will be obtained at ICU and hospital discharge.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
40
Neuromuscular electrical stimulation (30 minutes per day, 5 days/week) of the quadriceps femoris and gluteus maximus
Conventional physiotherapy with NMES device NOT activated
Unidad de Vigilancia Intensiva Respiratoria (UVIR)
Barcelona, Spain
RECRUITINGExercise capacity
Test sit-to-stand
Time frame: <48h from ICU discharge
Exercise capacity
Test sit-to-stand
Time frame: 24h before hospital discharge
Muscle strength
MRC score
Time frame: 1st day in which collaboration of the patient is ensured (through standardized 5 questions)
Muscle strength
MRC score
Time frame: <48 from ICU discharge
Muscle strength
MRC score
Time frame: 24h before hospital discharge
Muscle strength
Dynamometry
Time frame: 1st day in which collaboration of the patient is ensured (through standardized 5 questions)
Muscle strength
MRC score and dynamometry
Time frame: <48 from ICU discharge
Muscle strength
MRC score and dynamometry
Time frame: 24h before hospital discharge
Body composition (fat free mass)
Bioelectrical impedance
Time frame: <48h from inclusion
Body composition (fat free mass)
Bioelectrical impedance
Time frame: <48 from ICU discharge
Body composition (fat free mass)
Bioelectrical impedance
Time frame: 24h before hospital discharge
Functional Capacity
Barthel scale
Time frame: <24h from inclusion
Functional Capacity
Barthel scale
Time frame: 24h before hospital discharge
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