Emotional Brain Networks & Cognitive Functioning in Depression and Anxiety

University of Electronic Science and Technology of China105 enrolled

Overview

This study aims to 1) examine common and specific emotional and cognitive dysfunctions between Major Depression and generalized anxiety disorder; 2) Examine emotional and cognitive dysfunctions between the two disorders and healthy controls; 3) Examine the biomarkers predicting successful therapy or not.

Study Type

OBSERVATIONAL

Enrollment

105

Conditions

Major Depressive Disorder General Anxiety Disorder

Interventions

fMRIDEVICE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * GAD: 1. Diagnosis of Generalized Anxiety Disorder (GAD) according to DSM V criteria in a structured clinical interview for DSM-V Axis I disorders (SCID I; APA, 2014) and a confirmatory clinical interview 2. Duration of the current episode \> 3 weeks * MDD: 1. Diagnosis of current major depressive disorder in a structured clinical interview for DSM-V Axis I disorders (SCID I; APA, 2014) and a confirmatory clinical interview 2. Duration of the current episode \> 4 weeks Exclusion Criteria: * GAD: diagnosis of any other psychiatric Axis I disorder (except GAD) as a principal diagnosis within the past six months * MDD: diagnosis of any other psychiatric Axis I disorder (except MDD) as a principal diagnosis within the past six months

Locations (1)

School of Life Science and Technology, University of Electronic Science and Technology of China

Chengdu, Sichuan, China

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